Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Additional glycosylation within a specific hypervariable region of subtype 3a of hepatitis C virus protects against virus neutralization.

The Journal of infectious diseases - 1 Dec 2013

Anjum Sadia, Wahid Ahmed, Afzal Muhammad Sohail, Albecka Anna, Alsaleh Khaled, Ahmad Tahir, Baumert Thomas F, Wychowski Czeslaw, Qadri Ishtiaq, Penin François, Dubuisson Jean

Abstract excerpt

BACKGROUND: The envelope glycoprotein E2 of hepatitis C virus (HCV) contains several hypervariable regions. Interestingly, 2 regions of intragenotypic hypervariability within E2 have been described as being specific to HCV subtype 3a. Based on their amino acid position in E2, they were named HVR4...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Neutralizing
Share to Epitopes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycosylation

Share to Hepatitis C

Share to Hepatitis C Antibodies

Share to Pakistan

Share to Tetraspanin 28

Share to Viral Envelope Proteins

Source

Identifiers

PMID: 23908491
DOI: 10.1093/infdis/jit376

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23908491-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Additional glycosylation within a specific hypervariable region of subtype 3a of hepatitis C virus protects against virus neutralization.PMID 23908491Read ↗

Full-length characterization of hepatitis C virus subtype 3a reveals novel hypervariable regions under positive selection during acute infection.Semantic proximity Read ↗

HCV Envelope protein 2 sequence comparison of Pakistani isolate and In-silico prediction of conserved epitopes for vaccine development.Semantic proximity Read ↗

Identification of new functional regions in hepatitis C virus envelope glycoprotein E2.Semantic proximity Read ↗

Variation analysis of E1 and E2 in HCV subtypes.Semantic proximity Read ↗

Cloning, expression, and functional analysis of patient-derived hepatitis C virus glycoproteins.Semantic proximity Read ↗

A Diverse Panel of Hepatitis C Virus Glycoproteins for Use in Vaccine Research Reveals Extremes of Monoclonal Antibody Neutralization ResistanceSemantic proximity Read ↗

Inhibition of hepatitis C virus 3a genotype entry through Glanthus Nivalis Agglutinin.Semantic proximity Read ↗

Characterisation of the differences between hepatitis C virus genotype 3 and 1 glycoproteins.Semantic proximity Read ↗

Using evolutionary tools to refine the new hypervariable region 3 within the envelope 2 protein of hepatitis C virus.Semantic proximity Read ↗

Molecular epidemiology of hepatitis C virus genotype 4 isolates in Egypt and analysis of the variability of envelope proteins E1 and E2 in patients with chronic hepatitis.Semantic proximity Read ↗

Interplay of Host and Viral Genetic Variations in Modulating Antibody Responses to Genotype 3a Hepatitis C Virus: Implications for Vaccine DesignSemantic proximity Read ↗

Hypervariable region 1 shielding of hepatitis C virus is a main contributor to genotypic differences in neutralization sensitivity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.