Article
Inhibition of hepatitis C virus 3a genotype entry through Glanthus Nivalis Agglutinin.
Virology journal - 20 May 2011
Ashfaq Usman A, Masoud Muhammad S, Khaliq Saba, Nawaz Zafar, Riazuddin Sheikh
Abstract excerpt
BACKGROUND: Hepatitis C Virus (HCV) has two envelop proteins E1 and E2 which is highly glycosylated and play an important role in cell entry. Inhibition of virus at entry step is an important target to find antiviral drugs against HCV. Glanthus Nivalis Agglutinin (GNA) is a mannose binding lectin which has tendency for specific recognition and reversible binding to the sugar moieties of a wide variety of...
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