Article
Characterisation of the differences between hepatitis C virus genotype 3 and 1 glycoproteins.
Journal of medical virology - 1 Jul 2003
Shaw Megan L, McLauchlan John, Mills Peter R, Patel Arvind H, McCruden Elizabeth A B
Abstract excerpt
Sequence variation in the envelope E1 and E2 glycoproteins of hepatitis C virus (HCV) could account for differences in disease pathogenesis in patients infected with different genotypes. A cDNA encoding the structural region of the hepatitis C polyprotein was constructed to match the majority sequence of viral RNA extracted from a patient infected with genotype 3a (designated strain HCV3a-Gla). The principal...
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