Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HCV Envelope protein 2 sequence comparison of Pakistani isolate and In-silico prediction of conserved epitopes for vaccine development.

Journal of translational medicine - 30 Apr 2013

Idrees Sobia, Ashfaq Usman A, Khaliq Saba

Abstract excerpt

BACKGROUND: HCV is causing hundreds of cases yearly in Pakistan and has become a threat for Pakistani population. HCV E2 protein is a transmembrane protein involved in viral attachment and thus can serve as an important target for vaccine development but because of its variability, vaccine development against it has become a challenge. Therefore, this study was designed to isolate the HCV E2 gene from Pakistani...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Conserved Sequence
Share to Disulfides
Share to Epitopes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epitopes, B-Lymphocyte

Share to Epitopes, T-Lymphocyte

Share to Pakistan

Share to Protein Structure, Secondary

Share to Viral Envelope Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 23631455
DOI: 10.1186/1479-5876-11-105
PMCID: PMC3663723

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HCV Envelope protein 2 sequence comparison of Pakistani isolate and In-silico prediction of conserved epitopes for vaccine development.PMID 23631455Read ↗

In-silico analysis of putative HCV epitopes against Pakistani human leukocyte antigen background: An approach towards development of future vaccines for Pakistani population.Semantic proximity Read ↗

Hepatitis C Virus Subtype 3a Envelope Protein 1 Binding with Human Leukocyte Antigen Class I Types of Pakistani Population: Candidate Epitopes for Synthetic Peptide Vaccine.Semantic proximity Read ↗

Immuno-Informatics Analysis of Pakistan-Based HCV Subtype-3a for Chimeric Polypeptide Vaccine DesignSemantic proximity Read ↗

HCV genotyping and rational computational designing of an immunogenic multiepitope vaccine against genotype 3a.Semantic proximity Read ↗

Analysis of different HCV NS4B domains for the development of global consensus sequence.Semantic proximity Read ↗

Genetic Diversity Underlying the Envelope Glycoproteins of Hepatitis C Virus: Structural and Functional Consequences and the Implications for Vaccine Design.Semantic proximity Read ↗

Identification of T cell and B cell epitopes against Indian HCV-genotype-3a for vaccine development- An in silico analysis.Semantic proximity Read ↗

Hepatitis C virus genotypes in Pakistan: a systemic review.Semantic proximity Read ↗

Computational identification of a multi-peptide vaccine candidate in E2 glycoprotein against diverse Hepatitis C virus genotypes.Semantic proximity Read ↗

Comparison of structural architecture of HCV NS3 genotype 1 versus Pakistani genotype 3a.Semantic proximity Read ↗

Sequence and Structural Analysis of 3' Untranslated Region of Hepatitis C Virus, Genotype 3a, From Pakistani IsolatesSemantic proximity Read ↗

Molecular epidemiology of hepatitis C virus genotypes in different geographical regions of Punjab Province in Pakistan and a phylogenetic analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.