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Article

Variation analysis of E1 and E2 in HCV subtypes.

Archives of virology - 1 Oct 2015

Cheng Xue-Di, Xu Hua-Feng, Wei Xue-Mei, Zhou Hai-Zhou

Abstract excerpt

Pegylated interferon and ribavirin combination therapy effectively suppresses viral replication in 50 %-60 % of hepatitis C virus (HCV)-infected patients. However, HCV-infected patients often display varied responses to therapy, and strains of subtype lb (the most widespread HCV subtype worldwide) have more-severe clinical manifestations, greater viral loads, and poorer responses to interferon treatment....

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PMID: 26199129
DOI: 10.1007/s00705-015-2533-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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