Article
Role of calcium-dependent actin-bundling proteins: characterization of Dictyostelium mutants lacking fimbrin and the 34-kilodalton protein.
Cell motility and the cytoskeleton - 1 Dec 2005
Pikzack Claudia, Prassler Josef, Furukawa Ruth, Fechheimer Marcus, Rivero Francisco
Abstract excerpt
Actin-bundling proteins organize actin filaments into densely packed bundles. In Dictyostelium discoideum two abundant proteins display calcium-regulated bundling activity, fimbrin and the 34-kDa protein (ABP34). Using a GFP fusion we observed transient localization of fimbrin at the phagocytic cup and macropinosomes. The distribution of truncated constructs encompassing the EF hands and the first actin-binding...
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