Article
The apolipoprotein E e4 polymorphism is strongly associated with poor mobility performance test results but not self-reported limitation in older people.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Oct 2005
Melzer David, Dik M G, van Kamp Gerard J, Jonker Cees, Deeg Dorly J
Abstract excerpt
BACKGROUND: The apolipoprotein E (ApoE) e4 polymorphism is linked to increased mortality rates, Alzheimer's disease, and cardiovascular disease in older people, but previous studies have largely failed to detect an effect on self-reported mobility disability. We hypothesized that poor performance on mobility-related tests may provide a better measure of effects, and we aimed to estimate the extent to which the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.