Article
Performance of a population-based HIV-1 tropism phenotypic assay and correlation with V3 genotypic prediction tools in recent HIV-1 seroconverters.
Journal of acquired immune deficiency syndromes (1999) - 1 Jul 2008
de Mendoza Carmen, Van Baelen Kurt, Poveda Eva, Rondelez Evelien, Zahonero Natalia, Stuyver Lieven, Garrido Carolina, Villacian Jorge, Soriano Vincent
Abstract excerpt
BACKGROUND: Pure X4 and X4R5 dual-tropic viruses may be recognized in approximately 15% of drug-naive HIV-1-positive patients. CCR5 antagonists are active against R5 viruses; therefore, HIV tropism should be known before their prescription. PATIENTS AND METHODS: A population-based phenotypic assay was performed in 61 recent HIV-1 seroconverters. The results were compared with those obtained using 8 different...
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