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Article

Frequent CXCR4 tropism of HIV-1 subtype A and CRF02_AG during late-stage disease--indication of an evolving epidemic in West Africa.

Retrovirology - 22 Mar 2010

Esbjörnsson Joakim, Månsson Fredrik, Martínez-Arias Wilma, Vincic Elzbieta, Biague Antonio J, da Silva Zacarias J, Fenyö Eva Maria, Norrgren Hans, Medstrand Patrik

Abstract excerpt

BACKGROUND: HIV-1 is one of the fastest evolving pathogens, and is distinguished by geographic and genetic variants that have been classified into different subtypes and circulating recombinant forms (CRFs). Early in infection the primary coreceptor is CCR5, but during disease course CXCR4-using...

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Source

Open in PubMed Open full text

Identifiers

PMID: 20307309
DOI: 10.1186/1742-4690-7-23
PMCID: PMC2855529

Genes

CXCR4
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20307309-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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