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Article

Association of dietary and supplemental folate intake and polymorphisms in three FOCM pathway genes with colorectal cancer in a population-based case-control study.

Genes, chromosomes & cancer - 1 Oct 2013

Ashmore Joseph H, Lesko Samuel M, Muscat Joshua E, Gallagher Carla J, Berg Arthur S, Miller Paige E, Hartman Terryl J, Lazarus Philip

Abstract excerpt

Previous research has shown that greater intakes of dietary folate are associated with reduced risk for colorectal cancer (CRC) and that single nucleotide polymorphisms (SNPs) in genes involved in folate-mediated one-carbon metabolism (FOCM) also may be involved in altering CRC risk. The objective of this study was to evaluate the role of folate intake (and intakes of related dietary components such as...

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Source

Identifiers

PMID: 23893618
DOI: 10.1002/gcc.22089

Genes

MTHFD1
MTHFR
TYMS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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