Article
A genetic score can identify men at high risk for prostate cancer among men with prostate-specific antigen of 1-3 ng/ml.
European urology - 1 Jun 2014
Nordström Tobias, Aly Markus, Eklund Martin, Egevad Lars, Grönberg Henrik
Abstract excerpt
BACKGROUND: The diagnostic performance of a genetic score based on single nucleotide polymorphisms (SNPs) is unknown in the prostate-specific antigen (PSA) range of 1-3 ng/ml. A substantial proportion of men in this PSA span have prostate cancer (PCa), but biomarkers to determine who should undergo a prostate biopsy are lacking. OBJECTIVE: To evaluate whether a genetic risk score identifies men in the PSA range...
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