Article
Clinical validity and utility of genetic risk scores in prostate cancer.
Asian journal of andrology - 1 Jan 2000
Helfand Brian T, Kearns James, Conran Carly, Xu Jianfeng
Abstract excerpt
Current issues related to prostate cancer (PCa) clinical care (e.g., over-screening, over-diagnosis, and over-treatment of nonaggressive PCa) call for risk assessment tools that can be combined with family history (FH) to stratify disease risk among men in the general population. Since 2007, genome-wide association studies (GWASs) have identified more than 100 SNPs associated with PCa susceptibility. In this...
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