Article
Utility of incorporating genetic variants for the early detection of prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2009
Nam Robert K, Zhang William W, Trachtenberg John, Seth Arun, Klotz Laurence H, Stanimirovic Aleksandra, Punnen Sanoj, Venkateswaran Vasundara, Toi Ants, Loblaw D Andrew, Sugar Linda, Siminovitch Katherine A, Narod Steven A
Abstract excerpt
PURPOSE: Several single nucleotide polymorphisms (SNP) have been associated with the risk of prostate cancer. The clinical utility of using SNPs in the early detection of prostate cancer has not been evaluated. EXPERIMENTAL DESIGN: We examined a panel of 25 SNPs from candidate genes and chromosomal regions in 3,004 unselected men who were screened for prostate cancer using serum prostate-specific antigen (PSA)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
