Article
Prostate cancer screening in men aged 50-69 years (STHLM3): a prospective population-based diagnostic study.
The Lancet. Oncology - 1 Dec 2015
Grönberg Henrik, Adolfsson Jan, Aly Markus, Nordström Tobias, Wiklund Peter, Brandberg Yvonne, Thompson James, Wiklund Fredrik, Lindberg Johan, Clements Mark, Egevad Lars, Eklund Martin
Abstract excerpt
BACKGROUND: The prostate-specific antigen (PSA) test is used to screen for prostate cancer but has a high false-positive rate that translates into unnecessary prostate biopsies and overdiagnosis of low-risk prostate cancers. We aimed to develop and validate a model to identify high-risk prostate cancer (with a Gleason score of at least 7) with better test characteristics than that provided by PSA screening alone....
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