Article
Does genotyping of risk-associated single nucleotide polymorphisms improve patient selection for prostate biopsy when combined with a prostate cancer risk calculator?
The Prostate - 1 Apr 2014
Butoescu Valentina, Ambroise Jérôme, Stainier Annabelle, Dekairelle Anne-France, Gala Jean-Luc, Tombal Bertrand
Abstract excerpt
BACKGROUND: Genome-wide association studies have identified single nucleotide polymorphisms (SNPs) associated with higher risk of prostate cancer (PCa). This study aimed to evaluate whether published SNPs improve the performance of a clinical risk-calculator in predicting prostate biopsy result. METHODS: Three hundred forty-six patients with a previous prostate biopsy (191 positive, 155 negative) were enrolled....
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