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Article

Vitamin D suppression of endoplasmic reticulum stress promotes an antiatherogenic monocyte/macrophage phenotype in type 2 diabetic patients.

The Journal of biological chemistry - 9 Nov 2012

Riek Amy E, Oh Jisu, Sprague Jennifer E, Timpson Alexandra, de las Fuentes Lisa, Bernal-Mizrachi Leon, Schechtman Kenneth B, Bernal-Mizrachi Carlos

Abstract excerpt

Cardiovascular disease is the leading cause of morbidity/mortality in patients with type 2 diabetes mellitus (T2DM), but there is a lack of knowledge about the mechanism(s) of increased atherosclerosis in these patients. In patients with T2DM, the prevalence of 25-hydroxy vitamin D (25(OH)D) deficiency is almost twice that for nondiabetics and doubles the relative risk of developing cardiovascular disease...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23012375
DOI: 10.1074/jbc.M112.386912
PMCID: PMC3493893

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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