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Article

Palmitate promotes monocyte atherogenicity via de novo ceramide synthesis.

Free radical biology & medicine - 15 Aug 2012

Gao Dan, Pararasa Chathyan, Dunston Christopher R, Bailey Clifford J, Griffiths Helen R

Abstract excerpt

Elevated plasma free fatty acids (FAs) are associated with increased risk of cardiovascular disease. This study investigates the effects of the saturated FA palmitate and unsaturated FA oleate on monocyte phenotype and function. Incubation of human U937 and THP-1 monocytes with palmitate for 24h...

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Source

Identifiers

PMID: 22640955
DOI: 10.1016/j.freeradbiomed.2012.05.026

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22640955-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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