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Article

Lipopolysaccharide can block the potential of monocytes to differentiate into dendritic cells.

Journal of leukocyte biology - 1 Feb 1999

Palucka K A, Taquet N, Sanchez-Chapuis F, Gluckman J C

Abstract excerpt

We examined whether priming monocytes (MO) with lipopolysaccharide (LPS) influenced their further differentiation into either macrophages (Mphi) or dendritic cells (DC). LPS-primed MO differentiated into Mphi when cultured further with Mphi colony-stimulating factor (M-CSF) but, if cultured then with granulocyte/Mphi (GM)-CSF and IL-4 (interleukin-4), only about 30% of the cells differentiated into CD1a+ CD14- DC...

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PMID: 10088606
DOI: 10.1002/jlb.65.2.232

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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