Article
Effect of 1,25-dihydroxyvitamin D3 on induction of scavenger receptor and differentiation of 12-O-tetradecanoylphorbol-13-acetate-treated THP-1 human monocyte like cells.
Journal of cellular physiology - 1 Dec 1995
Suematsu Y, Nishizawa Y, Shioi A, Hino M, Tahara H, Inaba M, Morii H, Otani S
Abstract excerpt
We investigated the effect of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) on the expression of scavenger receptors in human monocytic cell line (THP-1 cells) treated for 24 h with 12-O-tetradecanoylphorbol-13-acetate (TPA) which induces their differentiation into macrophages. The capacity to degrade 125I-labeled acetyl low density lipoprotein (LDL) was developed in accordance with macrophage differentiation. The...
Topics
- Base Sequence
- Biomarkers
- Blotting, Northern
- Calcitriol
- Carboxylesterase
- Carboxylic Ester Hydrolases
- Cell Differentiation
- Down-Regulation
- Gene Expression
- Humans