Article

UPLC-ESI-MS based lipidomics revealed novel biomarkers in insulin receptor knockdown induced type 2 diabetes model of Drosophila

2026-08-20

Abstract excerpt

Type 2 diabetes (T2D) is a prevalent metabolic disorder affecting millions worldwide, characterized by insulin resistance and impaired glucose homeostasis. While mammalian models are widely used, Drosophila melanogaster provides a powerful alternative due to its conserved insulin signaling pathways, genetic tractability, and suitability for high throughput studies. In addition to glucose dysregulation, lipid metab...

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Literature Corpus work: 9fb6cd93-700e-5a72-a113-c527524536f4
DOI: 10.64898/2026.08.20.745875

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