Article
Adiponectin and adiponectin receptors in obesity-linked insulin resistance.
Novartis Foundation symposium - 1 Jan 2007
Kadowaki Takashi, Yamauchi Toshimasa, Kubota Naoto, Hara Kazuo, Ueki Kohjiro
Abstract excerpt
Adiponectin is an abundantly expressed adipokine in adipose tissue and has direct insulin sensitizing activity. We have proposed the following adiponectin hypothesis. Interactions of genetic factors such as single nucleotide polymorphisms (SNPs) in the Adiponectin gene and environmental factors causing obesity result in hypoadiponectinaemia, which appears to play an important causal role in obesity-linked insulin...
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