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Article

A glucagon-like endocrine pathway in Drosophila modulates both lipid and carbohydrate homeostasis.

The Journal of experimental biology - 1 Oct 2008

Bharucha K N, Tarr P, Zipursky S L

Abstract excerpt

The regulation of energy homeostasis is fundamental to all organisms. The Drosophila fat body serves as a repository for both triglycerides and glycogen, combining the energy storage functions of mammalian adipose and hepatic tissues, respectively. Here we show that mutation of the Drosophila adipokinetic hormone receptor (AKHR), a functional analog of the mammalian glucagon receptor, leads to abnormal...

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Identifiers

PMID: 18805809
DOI: 10.1242/jeb.016451
PMCID: PMC2714167

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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