Article
Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.
The Journal of clinical investigation - 1 Jul 2006
Kadowaki Takashi, Yamauchi Toshimasa, Kubota Naoto, Hara Kazuo, Ueki Kohjiro, Tobe Kazuyuki
Abstract excerpt
Adiponectin is an adipokine that is specifically and abundantly expressed in adipose tissue and directly sensitizes the body to insulin. Hypoadiponectinemia, caused by interactions of genetic factors such as SNPs in the Adiponectin gene and environmental factors causing obesity, appears to play an important causal role in insulin resistance, type 2 diabetes, and the metabolic syndrome, which are linked to...
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