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Article

Genomic analysis of natural selection and phenotypic variation in high-altitude mongolians.

PLoS genetics - 1 Jan 2013

Xing Jinchuan, Wuren Tana, Simonson Tatum S, Watkins W Scott, Witherspoon David J, Wu Wilfred, Qin Ga, Huff Chad D, Jorde Lynn B, Ge Ri-Li

Abstract excerpt

Deedu (DU) Mongolians, who migrated from the Mongolian steppes to the Qinghai-Tibetan Plateau approximately 500 years ago, are challenged by environmental conditions similar to native Tibetan highlanders. Identification of adaptive genetic factors in this population could provide insight into coordinated physiological responses to this environment. Here we examine genomic and phenotypic variation in this unique...

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Share to Acclimatization
Share to Adaptation, Physiological

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Altitude

Share to Altitude Sickness

Share to Genetics, Population

Share to Genome, Human

Share to Mongolia

Share to Selection, Genetic

Source

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Identifiers

PMID: 23874230
DOI: 10.1371/journal.pgen.1003634
PMCID: PMC3715426

Genes

EDAR
EPAS1
PKLR
PPARG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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