Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Distinct allelic patterns of nanog expression impart embryonic stem cell population heterogeneity.

PLoS computational biology - 1 Jan 2013

Wu Jincheng, Tzanakakis Emmanuel S

Abstract excerpt

Nanog is a principal pluripotency regulator exhibiting a disperse distribution within stem cell populations in vivo and in vitro. Increasing evidence points to a functional role of Nanog heterogeneity on stem cell fate decisions. Allelic control of Nanog gene expression was reported recently in mouse embryonic stem cells. To better understand how this mode of regulation influences the observed heterogeneity of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Embryonic Stem Cells
Share to Gene Expression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to NANOG gene

Share to Homeodomain Proteins

Share to Nanog Homeobox Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 23874182
DOI: 10.1371/journal.pcbi.1003140
PMCID: PMC3708867

Genes

NANOG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Distinct allelic patterns of nanog expression impart embryonic stem cell population heterogeneity.PMID 23874182Read ↗

Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells.Semantic proximity Read ↗

Transcription factor heterogeneity in pluripotent stem cells: a stochastic advantage.Semantic proximity Read ↗

TGF-β-superfamily signaling regulates embryonic stem cell heterogeneity: self-renewal as a dynamic and regulated equilibrium.Semantic proximity Read ↗

Control of ground-state pluripotency by allelic regulation of Nanog.Semantic proximity Read ↗

Stochastic promoter activation affects Nanog expression variability in mouse embryonic stem cells.Semantic proximity Read ↗

Time scales in epigenetic dynamics and phenotypic heterogeneity of embryonic stem cells.Semantic proximity Read ↗

A model-based analysis of culture-dependent phenotypes of mESCs.Semantic proximity Read ↗

Concise Review: Pursuing Self-Renewal and Pluripotency with the Stem Cell Factor NanogSemantic proximity Read ↗

Single-Cell Analyses of ESCs Reveal Alternative Pluripotent Cell States and Molecular Mechanisms that Control Self-Renewal.Semantic proximity Read ↗

Functional Separation of mRNA Domains Coordinates Pluripotent Cell BehaviorSemantic proximity Read ↗

Nanog safeguards pluripotency and mediates germline development.Semantic proximity Read ↗

Hematopoietic differentiation is characterized by a transient peak of entropy at a single-cell levelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.