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Article

TGF-β-superfamily signaling regulates embryonic stem cell heterogeneity: self-renewal as a dynamic and regulated equilibrium.

Stem cells (Dayton, Ohio) - 1 Jan 2013

Galvin-Burgess Katherine E, Travis Emily D, Pierson Kelsey E, Vivian Jay L

Abstract excerpt

Embryonic stem cells dynamically fluctuate between phenotypic states, as defined by expression levels of genes such as Nanog, while remaining pluripotent. The dynamic phenotype of stem cells is in part determined by gene expression control and dictated by various signaling pathways and transcriptional regulators. We sought to define the activities of two TGF-β-related signaling pathways, bone morphogenetic...

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PMID: 23081664
DOI: 10.1002/stem.1252
PMCID: PMC3528825

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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