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Article

Time scales in epigenetic dynamics and phenotypic heterogeneity of embryonic stem cells.

PLoS computational biology - 1 Jan 2013

Sasai Masaki, Kawabata Yudai, Makishi Koh, Itoh Kazuhito, Terada Tomoki P

Abstract excerpt

A remarkable feature of the self-renewing population of embryonic stem cells (ESCs) is their phenotypic heterogeneity: Nanog and other marker proteins of ESCs show large cell-to-cell variation in their expression level, which should significantly influence the differentiation process of individua...

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Identifiers

PMID: 24348228
DOI: 10.1371/journal.pcbi.1003380
PMCID: PMC3861442

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24348228-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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