Article
Methods for quantification of pore-voltage sensor interaction in Ca(V)1.2.
Pflugers Archiv : European journal of physiology - 1 Feb 2014
Beyl S, Kügler P, Hohaus A, Depil K, Hering S, Timin E
Abstract excerpt
Voltage sensors (VSs) initiate the pore opening and closure in voltage-gated ion channels. Here, we propose a technique for estimation of the equilibrium constant of the up- and downward VS movements and rate constants of pore transitions from macroscopic current kinetics. Bell-shaped voltage dep...
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