Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structural determinants of voltage-gating properties in calcium channels.

eLife - 30 Mar 2021

Fernández-Quintero Monica L, El Ghaleb Yousra, Tuluc Petronel, Campiglio Marta, Liedl Klaus R, Flucher Bernhard E

Abstract excerpt

Voltage-gated calcium channels control key functions of excitable cells, like synaptic transmission in neurons and the contraction of heart and skeletal muscles. To accomplish such diverse functions, different calcium channels activate at different voltages and with distinct kinetics. To identify the molecular mechanisms governing specific voltage sensing properties, we combined structure modeling, mutagenesis,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium
Share to Calcium Channels, L-Type
Share to Ion Channel Gating

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Markov Chains

Share to Membrane Potentials

Share to Molecular Dynamics Simulation

Share to Rabbits

Share to Structure-Activity Relationship

Source

Open in PubMed Open full text

Identifiers

PMID: 33783354
DOI: 10.7554/eLife.64087
PMCID: PMC8099428

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structural determinants of voltage-gating properties in calcium channels.PMID 33783354Read ↗

Voltage-dependent calcium channels: from structure to function.Semantic proximity Read ↗

Structural basis of voltage-dependent gating in BK channels.Semantic proximity Read ↗

Fifty years of gating currents and channel gating.Semantic proximity Read ↗

CaV1.1 voltage-sensing domain III exclusively controls skeletal muscle excitation-contraction coupling.Semantic proximity Read ↗

Tracking a complete voltage-sensor cycle with metal-ion bridges.Semantic proximity Read ↗

A theoretical model for calculating voltage sensitivity of ion channels and the application on Kv1.2 potassium channel.Semantic proximity Read ↗

The differential impacts of equivalent gating-charge mutations in voltage-gated sodium channels.Semantic proximity Read ↗

Voltage-gated calcium channels in genetic diseases.Semantic proximity Read ↗

Mechanisms Responsible for ω-Pore Currents in Cav Calcium Channel Voltage-Sensing Domains.Semantic proximity Read ↗

Mechanism of voltage sensing in Ca2+- and voltage-activated K+ (BK) channels.Semantic proximity Read ↗

Voltage-dependent calcium channels: structures and drug-binding sites.Semantic proximity Read ↗

Identification of the modulatory Ca2+-binding sites of acid-sensing ion channel 1a.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.