Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

UDP-glucuronosyltransferase 2B17 genotype and the risk of lung cancer among Austrian Caucasians.

Cancer epidemiology - 1 Oct 2013

Gruber Michaela, Le Trang, Filipits Martin, Gsur Andrea, Mannhalter Christine, Jäger Ulrich, Vanura Katrina

Abstract excerpt

BACKGROUND: The enzyme uridine diphospho glucuronosyltansferase 2B17 (UGT2B17) glucuronidates several endogenous and exogenous compounds, including carcinogens from tobacco smoke like 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanl (NNAL). UGT2B17 shows a remarkable copy number variation (CNV) and an association between deletion genotype and increased risk of lung adenocarcinoma in women has been previously...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Austria
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Dosage

Share to Glucuronosyltransferase

Share to Lung Neoplasms

Share to Minor Histocompatibility Antigens

Share to Smoking

Share to White People

Source

Identifiers

PMID: 23850147
DOI: 10.1016/j.canep.2013.06.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

UDP-glucuronosyltransferase 2B17 genotype and the risk of lung cancer among Austrian Caucasians.PMID 23850147Read ↗

The UDP-glucuronosyltransferase 2B17 gene deletion polymorphism: sex-specific association with urinary 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol glucuronidation phenotype and risk for lung cancer.Semantic proximity Read ↗

Characterization of UDP-glucuronosyltransferase 2A1 (UGT2A1) variants and their potential role in tobacco carcinogenesis.Semantic proximity Read ↗

Association between Glucuronidation Genotypes and Urinary NNAL Metabolic Phenotypes in Smokers.Semantic proximity Read ↗

Association between UGT1A1*28*28 genotype and lung cancer in the Japanese population.Semantic proximity Read ↗

Homozygous deletions of UGT2B17 modifies effects of smoking on TP53-mutations and relapse of head and neck carcinoma.Semantic proximity Read ↗

UDP-glucuronosyltransferase 1A10: activity against the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a potential role for a novel UGT1A10 promoter deletion polymorphism in cancer susceptibility.Semantic proximity Read ↗

Tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with orolaryngeal cancer risk.Semantic proximity Read ↗

UGT1A6 polymorphisms modulated lung cancer risk in a Chinese population.Semantic proximity Read ↗

CYP1A2 genetic polymorphisms and adenocarcinoma lung cancer risk in the Tunisian population.Semantic proximity Read ↗

Beta-2 adrenergic receptor gene (ADRB2) polymorphism and risk for lung adenocarcinoma: a case-control study in a Chinese population.Semantic proximity Read ↗

Genetic polymorphisms of human UDP-glucuronosyltransferase (UGT) genes and cancer risk.Semantic proximity Read ↗

Meta-analysis reveals a lack of association between UGT2B17 deletion polymorphism and tumor susceptibility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.