Article
Meta-analysis reveals a lack of association between UGT2B17 deletion polymorphism and tumor susceptibility.
PloS one - 1 Jan 2014
Deng Xiaheng, Cheng Yidong, Yang Xiao, Li Shuang, Zhao Ruizhe, Liu Kang, Liu Jinliang, Cao Qiang, Qin Chao, Shao Pengfei, Meng Xiaoxin, Li Jie, Lu Qiang, Yin Changjun
Abstract excerpt
PURPOSE: UGT2B17 is a vital member of the UGT2 family and functions as a detoxification enzyme which catalyzes the glucuronidation of lipophilic compounds. Accumulating evidences implicates that it may contribute to the susceptibility of tumor risk. Identification of a UGT2B17 deletion polymorphism has attracted studies to evaluate the association between the UGT2B17 deletion polymorphism and tumor risk in...
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