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Article

Characterization of UDP-glucuronosyltransferase 2A1 (UGT2A1) variants and their potential role in tobacco carcinogenesis.

Pharmacogenetics and genomics - 1 Feb 2011

Bushey Ryan T, Chen Gang, Blevins-Primeau Andrea S, Krzeminski Jacek, Amin Shantu, Lazarus Philip

Abstract excerpt

OBJECTIVE: To examine UGT2A1 expression in human tissues, determine its glucuronidation activity against tobacco carcinogens, and assess the potential functional role of UGT2A1 missense single nucleotide polymorphisms on UGT2A1 enzyme activity. METHODS: Reverse transcription polymerase chain reac...

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Identifiers

PMID: 21164388
DOI: 10.1097/FPC.0b013e328341db05
PMCID: PMC3019304

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21164388-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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