Article
[Interleukin-1 and the interleukin-1 receptor antagonist gene polymorphisms study in patients with rheumatoid arthritis].
Pathologie-biologie - 1 Dec 2013
Allam I, Djidjik R, Ouikhlef N, Louahchi S, Raaf N, Behaz N, Abdessemed A, Khaldoun N, Tahiat A, Bayou M, Ladjouze-Rezig A, Ghaffor M
Abstract excerpt
OBJECTIVES: One of the most important pro-inflammatory cytokines in the pathophysiology of rheumatoid arthritis (RA) is interleukin 1 (IL-1). The purpose of this study is to evaluate the association between IL-1B (-511), IL-1 (+3953), IL-1 RN variable number of tandem repeat (VNTR) polymorphisms and the occurrence in Algerian patients with rheumatoid arthritis. We also analyze their correlations with clinical and...
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