Article
Rheumatoid arthritis and genetic variations in cytokine genes: a population-based study in Kashmir Valley.
Immunological investigations - 1 Jan 2014
Shafia Syed, Dilafroze, Sofi Fayaz A, Rasool Roohi, Javeed Sheikh, Shah Zafar Amin
Abstract excerpt
OBJECTIVE: The aim of our study was to determine the genetic associations between polymorphisms of the IL1β gene (-511C/T and +3953C/T) and IL6 gene (-174G/C) with disease susceptibility and severity in patients with rheumatoid arthritis (RA) in ethnic Kashmiri population. METHODS: Allele and genotype frequencies of IL1β -511 C/T, IL1β +3953 C/T and IL6 -174 G/C polymorphisms were compared between 150 RA patients...
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