Article
Interleukin-1beta and interleukin-1 receptor antagonist gene polymorphisms in rheumatoid arthritis.
Scandinavian journal of rheumatology - 1 Jan 2001
Huang C M, Tsai F J, Wu J Y, Wu M C
Abstract excerpt
The purpose of this study was to evaluate if IL-1beta (IL-1beta promoter and IL-1beta exon 5) and IL-1receptor antagonist (IL-1Ra) gene polymorphisms act as markers of susceptibility to or severity of RA. The study included 104 RA patients and 103 normal controls. No significant difference was observed in the cytokine allelic frequencies of IL-1beta promoter and IL-1beta exon 5 between patients with RA and...
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