Article
Interleukin-1β, Interleukin1-Ra, Interleukin-10, and tumor necrosis factor-α polymorphisms in Tunisian patients with rheumatoid arthritis.
Pathologie-biologie - 1 Sept 2015
Lagha A, Zidi S, Stayoussef M, Gazouani E, Kochkar R, Kochbati S, Almawi W Y, Yacoubi-Loueslati B
Abstract excerpt
OBJECTIVES: The aim of this study was to investigate the role of IL-1β (-511C>T), TNFα (-308 G>A), IL-10 (-1082 G>A) and IL-1RN VNTR polymorphisms in the susceptibility to rheumatoid arthritis (RA) in Tunisians. PATIENTS AND METHODS: Using PCR-based methods, 104 RA patients and 150 healthy controls were investigated. We compared allele and genotype frequencies in RA patients versus controls and analyzed their...
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