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Article

IL-1B and IL-1RN gene polymorphisms in rheumatoid arthritis: relationship with protein plasma levels and response to therapy.

Pharmacogenomics - 1 Jul 2006

Tolusso Barbara, Pietrapertosa Donatello, Morelli Alessia, De Santis Maria, Gremese Elisa, Farina Giuseppina, Carniello Siro Giorgio, Del Frate Marino, Ferraccioli Gianfranco

Abstract excerpt

OBJECTIVES: To analyze the association of interleukin (IL-1) gene polymorphisms with susceptibility to, and severity of, rheumatoid arthritis (RA) patients, comparing them with the genotype distribution in healthy controls. Also, to assess the influence of IL1-B and IL1RN gene polymorphism on IL-1beta/IL-1Ra plasma levels and response to therapy. PATIENTS AND METHODS: We tested the allelic distribution of IL-1B...

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PMID: 16886894
DOI: 10.2217/14622416.7.5.683

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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