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Article

Structural analysis of protein Z gene variants in patients with foetal losses.

Thrombosis and haemostasis - 1 Sept 2013

Caliandro R, Nico G, Tiscia G, Favuzzi G, De Stefano V, Rossi E, Margaglione M, Grandone E

Abstract excerpt

The role of protein Z (PZ) in the etiology of human disorders is unclear. A number of PZ gene variants, sporadic or polymorphic and found exclusively in the serine protease domain, have been observed. Crystal structures of PZ in complex with the PZ-dependent inhibitor (PZI) have been recently obtained. The aim of this study was a structural investigation of the serine protease PZ domain, aiming at finding common...

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Identifiers

PMID: 23846529
DOI: 10.1160/TH13-01-0005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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