Article
Protein Z variants associated with protein Z plasma levels and with risk of idiopathic recurrent miscarriage.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Sept 2013
Al-Shaikh Fatima S, Sater Mai S, Finan Ramzi R, Racoubian Eddie, Abu-Hijleh Tala M, Mustafa Fekria E, Almawi Wassim Y
Abstract excerpt
Protein Z (PZ) deficiency due to anti-PZ autoantibodies and/or mutations in PZgene was linked with adverse pregnancy outcomes, including idiopathic recurrent miscarriage (IRM). We investigated the association of rs3024718, rs3024719, rs3024731, rs3024778, rs3024772, and (G79A) PZ variants and changes in PZ levels in 287 women with IRM, and 308 control women. Of the 6 single nucleotide polymorphisms...