Article
Impact of hepatitis B virus integration into liver tissue on the efficacy of peginterferon and ribavirin therapy in hepatitis B virus-negative chronic hepatitis C patients.
Journal of clinical gastroenterology - 1 Jan 2014
Toyoda Hidenori, Kumada Takashi, Tada Toshifumi, Murakami Yoshiki
Abstract excerpt
BACKGROUND: Integration of hepatitis B virus (HBV) DNA into host hepatic DNA is found in patients without HBV surface antigen (HBsAg). We investigated the prevalence of HBV integration and its association with the outcome of peginterferon (PEG-IFN) and ribavirin combination therapy in HBsAg-negative chronic hepatitis C patients. STUDY: We analyzed 157 patients chronically infected with hepatitis C virus (HCV)...
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