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Article

Direct sequencing is a reliable assay with good clinical applicability for KRAS mutation testing in colorectal cancer.

Cancer biomarkers : section A of Disease markers - 1 Jan 2013

Wang Jianfei, Yang Hongying, Shen Yinchen, Wang Shuai, Lin Dongmei, Ma Li, Han Xiaohong, Shi Yuankai

Abstract excerpt

BACKGROUND: The analysis of KRAS mutations in colorectal cancer (CRC) has made the need urgent for a reliable and easy to implement assay in daily practice. OBJECTIVE: This study was designed to compare the different assays for KRAS testing and elucidate its mutation status in Chinese CRC patients. METHODS: Direct sequencing was conducted to detect mutations in KRAS codons 12, 13 and 61 using 574 colorectal...

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Identifiers

PMID: 23838137
DOI: 10.3233/CBM-130334
PMCID: PMC12928280

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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