Article
The influence of single and combined IL28B polymorphisms on response to treatment of chronic hepatitis C.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Sept 2013
Lazarevic Ivana, Djordjevic Jelena, Cupic Maja, Karalic Danijela, Delic Dragan, Svirtlih Neda, Simonovic Jasmina, Svorcan Petar, Milic Natasa, Jovanovic Tanja
Abstract excerpt
BACKGROUND: Three single nucleotide polymorphisms (SNPs) near IL28B gene were shown to be highly predictive of sustained virological response (SVR) in patients with chronic hepatitis C virus (HCV) infection. OBJECTIVES: This study attempted to demonstrate the role of single and combined IL28B polymorphisms (rs8099917, rs12979860 and rs12980275) and other host and viral factors in predicting response to treatment,...
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