Article
Genetic polymorphisms of IL28b gene as predictors of response to dual therapy in genotypes 1 and 4-HCV and HIV/HCV-infected patients.
The new microbiologica - 1 Oct 2015
Sticchi Laura, Di Biagio Antonio, Sartini Marina, Rappazzo Emanuela, Nicolini Laura A, Cenderello Giovanni, Valle Caterina, Azzola Emilio, Grasso Alessandro, De Leo Pasqualina, Boldrini Alessandra, Setti Maurizio, Prinapori Roberta, Lorusso Carolina, Bruzzone Bianca, Icardi Giancarlo
Abstract excerpt
We describe the genotypes and allele distribution of interleukin 28B (IL28B) rs12979860 and rs8099917 single nucleotide polymorphisms (SNPs) in hepatitis C virus (HCV) G1-4 infected patients, to assess predictive ability and to determine whether the combined determination of two IL28B SNPs might improve sustained virologic response (SVR) prediction of both in HCV mono- and HIV/HCV co-infected patients. IL28B SNPs...
Read the complete abstract on PubMed