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Article

Strong prediction of virological response to combination therapy by IL28B gene variants rs12979860 and rs8099917 in chronic hepatitis C genotype 4.

Liver international : official journal of the International Association for the Study of the Liver - 1 Jul 2014

Ragheb Mostafa M, Nemr Nader A, Kishk Rania M, Mandour Mohamed F, Abdou Mohamed M, Matsuura Kentaro, Watanabe Tsunamasa, Tanaka Yasuhito

Abstract excerpt

BACKGROUND: A strong association between single nucleotide polymorphisms (SNPs) of IL28B and treatment outcomes of pegylated interferon-α (PEG IFNα) and ribavirin (RBV) has been shown in chronic hepatitis C (CHC) patients with genotype 1. AIM: This study aimed to assess two SNPs of IL28B, rs12979860 and rs8099917, in predicting sustained virological responses (SVR) to treatment of CHC patients with genotype 4...

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Identifiers

PMID: 24102823
DOI: 10.1111/liv.12321

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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