Article
Impact of IL28B genotype on the early and sustained virologic response in treatment-naïve patients with chronic hepatitis C.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Apr 2011
Stättermayer Albert Friedrich, Stauber Rudolf, Hofer Harald, Rutter Karoline, Beinhardt Sandra, Scherzer Thomas Matthias, Zinober Kerstin, Datz Christian, Maieron Andreas, Dulic-Lakovic Emina, Kessler Harald H, Steindl-Munda Petra, Strasser Michael, Krall Christoph, Ferenci Peter
Abstract excerpt
BACKGROUND & AIMS: Single nucleotide polymorphisms (SNPs) in the gene that encodes interleukin (IL)-28B predict response of patients with chronic hepatitis C to antiviral therapy. We investigated the roles of polymorphisms rs12979860 and rs8099917 on the early virologic response of treatment-naïve patients. METHODS: SNPs were identified by real-time polymerase chain reaction analysis of samples from 682 patients...
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