Article
A single IL28B genotype SNP rs12979860 determination predicts treatment response in patients with chronic hepatitis C Genotype 1 virus.
European journal of gastroenterology & hepatology - 1 Oct 2011
Halfon Philippe, Bourliere Marc, Ouzan Denis, Maor Yaakov, Renou Christophe, Wartelle Claire, Pénaranda Guillaume, Tran Albert, Botta Danielle, Oules Valérie, Castellani Paul, Portal Isabelle, Argiro Laurent, Dessein Alain
Abstract excerpt
BACKGROUND: Recent studies have suggested that host genetics may be useful for predicting drug response and have supported the recommendation that single polynucleotide polymorphisms (SNPs) of IL28B should be investigated when treating hepatitis C virus (HCV)-1 infected patients. The aim of this study was to determine whether a single IL-28B genotype SNP rs8099917 or rs12979860 determination is sufficient to...
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