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Article

Overview of enzymes of drug metabolism.

Journal of pharmacokinetics and biopharmaceutics - 1 Oct 1996

Meyer U A

Abstract excerpt

Most pharmacologically active molecules are lipophilic and remain un-ionized or only partially ionized at physiological pH. Biotransformation means that a lipid-soluble xenobiotic or endobiotic compound is enzymatically transformed into polar, water-soluble, and excretable metabolites. The major...

Topics

Biotransformation
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System
Enzyme Induction
Genetic Variation
Humans
In Vitro Techniques
Liver
Microsomes, Liver
Pharmaceutical Preparations
Polymorphism, Genetic

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Identifiers

PMID: 9131484
DOI: 10.1007/BF02353473

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9131484-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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