Article
Low prevalence of germline PALB2 mutations in Australian triple-negative breast cancer.
International journal of cancer - 15 Jan 2014
Wong-Brown Michelle W, Avery-Kiejda Kelly A, Bowden Nikola A, Scott Rodney J
Abstract excerpt
Triple-negative breast cancer (TNBC) is a tumour classification that is defined by oestrogen receptor, progesterone receptor and human epidermal growth factor receptor 2 receptor negativity. TNBCs share a similar gene expression profile to BRCA-mutated tumours, have been shown to carry a high proportion of BRCA mutations and have a more adverse prognosis compared to other types of breast tumours. PALB2 has been...
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