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Article

Prevalence of PALB2 mutations in Australian familial breast cancer cases and controls.

Breast cancer research : BCR - 19 Aug 2015

Thompson Ella R, Gorringe Kylie L, Rowley Simone M, Wong-Brown Michelle W, McInerny Simone, Li Na, Trainer Alison H, Devereux Lisa, Doyle Maria A, Li Jason, Lupat Richard, Delatycki Martin B, Mitchell Gillian, James Paul A, Scott Rodney J, Campbell Ian G

Abstract excerpt

INTRODUCTION: PALB2 is emerging as a high-penetrance breast cancer predisposition gene in the order of BRCA1 and BRCA2. However, large studies that have evaluated the full gene rather than just the most common variants in both cases and controls are required before all truncating variants can be included in familial breast cancer variant testing. METHODS: In this study we analyse almost 2000 breast cancer cases...

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Source

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Identifiers

PMID: 26283626
DOI: 10.1186/s13058-015-0627-7
PMCID: PMC4539664

Genes

PALB2
BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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