Article
Genotype-dependent radiosensitivity: clonogenic survival, apoptosis and cell-cycle redistribution.
International journal of radiation biology - 1 Feb 2008
Williams Jerry R, Zhang Yonggang, Zhou Haoming, Russell James, Gridley Daila S, Koch Cameron J, Little John B
Abstract excerpt
PURPOSE: We describe variations of three radiation-induced endpoints on the basis of cell genotype: Clonogenic survival, expression of apoptosis and cell-cycle redistribution. METHODS: Clonogenic survival, apoptosis and cell-cycle redistribution are measured in multiple cell lines after exposure to radiation between 2 and 16 Gy. Cell lines varied in clonogenic radiosensitivity and expression of specific genes....
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